Recurrent thromboses are extremely dangerous conditions, in which there is a blockage of the vascular bed. They can lead to serious consequences, including death. Hereditary thrombophilia is a disease that has the development of the described pathology. It is quite common, especially in adult women, so it's important to pay attention to anxious symptoms in time and always consult a doctor.
Examination of hereditary thrombophilia
The main problem in detecting the disease under consideration is that the carrier of the causative gene can not guess its presence. As a rule, noticeable pathological changes in the body are found after injuries, with the growth of cancer tumors, the intake of hormonal drugs, including contraceptives, in case of abnormalities in the endocrine system, and during pregnancy.
If there is a suspicion of progression of this disease, you should undergo a comprehensive laboratory examination. In the diagnosis of hereditary thrombophilia, a search is made for markers responsible for the development of pathology. Usually, eight factors of hemostasis are analyzed, each of which can lead to an increase in blood viscosity and the formation of thrombi.
Criteria for assessing predisposition to hereditary thrombophilia indicating the norm (in parentheses):
- blood coagulation factor II or F2-prothrombin (G / G);
- F5 (G / G);
- F7 (G / G);
- F13A1 (G / G);
- FGB-fibrinogen (G / G);
- an antagonist of a tissue plasminogen activator, serpin-1 or PAI-1 (5G / 5G);
- a platelet receptor for collagen fibers or ITGA2-a2 integrin (C / C);
- a platelet receptor for fibrinogen or ITGB3-b integrin (T / T).
Symptoms of hereditary thrombophilia
The signs of the described disease depend on the localization of the blood clots. The presence of pathology is indicated by the following conditions:
- infarcts of internal organs;
- repeated multiple thromboses of different locations;
- thromboembolism, especially in the pool of pulmonary arteries;
- blockage of veins of extremities;
- thrombophlebitis;
- varicose veins and others.
At the slightest suspicion of the possibility of developing thrombophilia, it is necessary to urgently appeal to a phlebologist and undergo an appointed medical examination. Timely detection of the disease will help prevent many serious complications and dangerous pathologies.