Adelfan - analogues in composition

All hypertensive patients are well aware that drugs for lowering blood pressure need to be taken regularly, only in this way one can keep well for a long time. For more than one decade, Adelphan has been used for this purpose. But this medicine has many drawbacks, in the first place - causes heart disease. Let's find out which analogues of Adelfan in composition do not have similar contraindications.

Composition of Adelfan and the main disadvantages of the drug

Medication Adelfan refers to complex means that regulate blood pressure. And those who have the property to change throughout the day, this drug is not recommended. Adelphan is best suited to hypertensive patients with a constant slight increase in pressure, the causes of which are not established. In those cases when doctors manage to calculate the factor that causes hypertension, medical drugs that directly affect it are used. In other cases, Adelphan is used.

The main active substance of Adelfan is reserpine. This component refers to sympatolics, that is, reagents that affect the sympathetic part of the autonomic nervous system. Reserpine slows the transmission of the brain's nervous impulse to the heart, as a result of which the number of its contractions decreases, the pulse decreases and the blood moves more slowly through the vessels. This results in a reduction in pressure. The second component of the drug is dihydralysin. It is myotropic spasmolytic, that is, a substance that relaxes the smooth muscles of blood vessels, mostly arterial. Reduction of vascular resistance expands their walls, they become more elastic and the blood flow passes better.

Due to the complex effect of reserpine and dihydralysin, it is possible to achieve a long-term reduction in blood pressure. But these substances have a lot of contraindications:

Also Adelfan therapy can not be combined with the use of MAO inhibitors, electroconvulsive therapy and the use of muscle relaxants. All these reasons are the reason for the search for a substitute Adelphan, which people with these diseases could use without a threat to health.

Composition of Adelfan-Ezidrex and its advantages

The most successful analogue of Adelfan is the medical preparation Adelfan-Ezidreks. It contains the main components of Adelfan - reserpine and dihydralysin - as well as a substance that reduces their negative effects on the body, hydrochlorothiazide. This is a thiazide diuretic, which slows the reabsorption of sodium and chlorine ions, which positively affects the excretory functions of the kidneys. As a result, the drug is almost completely removed from the body during the day and does not have time to badly affect the work of internal organs, cause side effects.

Indications for the use of this drug are the same as Adelphan, but the side effects are much less. It:

In general, the drug is well tolerated and can be used in therapy for the elderly and people with poor health. More successful analogues of Adelfan-Ezidreks have not been established to date, the medicine is a modern version of the obsolete Adelfan and is actively used in the treatment of patients with hypertension all over the world.