One of the most important studies that can warn a pregnant woman about dangerous hereditary diseases is a chorionic biopsy.
We will reveal the essence of the process - a chorionic villus biopsy is a special test that allows diagnosing a child's condition at the time of testing. It is performed during pregnancy at the 9-12 embryonic weeks under the supervision of ultrasound. The results of a chorion biopsy can be obtained after 2-3 days. Puncture of the chorion is taken in the volume of 1-15 mg at the frequency of obtaining the required amount for the analysis of villus chorion: 94-99.5%.
Indications and contraindications for the analysis of villus chorion
The test allows to identify in advance possible problems associated with the genetics of the child. Especially important is the test in the presence of hereditary diseases in the relatives of the future mother or father of the fetus.
Indication for the test:
- age of expectant mother 35 years and older;
- carriage of a gene mutation or a chromosomal abnormality;
- results of sonography;
- The measurements of the collar space are less than 3 mm in 10-14 weeks.
Also an indication for taking puncture is an overburdened genetic or obstetric anamnesis (the presence in the anamnesis of the conclusion that the child can be born with VLP, monogenic or chromosomal disease).
Contraindication to the test can be:
- feverish condition of a woman;
- blood discharge from the genital tract;
- exacerbation of chronic diseases;
- severe incompetence of the cervix;
- inaccessibility of chorionic tissue;
- infectious lesion of the skin of the anterior abdominal wall;
- pronounced adhesion process in the small pelvis.
Chorion analysis
The analysis of the chorion is a biopsy of the villi of the chorion, namely, the outer membrane covered with villi. Can be carried out by transcervical and transabdominal methods. Transcervical variant is a fence of the villi by a catheter or biopsy forceps through the cervix. In the transabdominal method, samples are taken through the anterior abdominal cavity with a long thin needle. The choice of method depends on the location of the chorion in the uterus.
Who made the chorionic biopsy, knows that the analysis of the villus of the chorion, mainly in the early stages of pregnancy, guarantees a quick result, a DNA test (the test for paternity) and the determination of the sex of the fetus .
Chorion biopsy - possible consequences
Practice shows that a biopsy of the chorionic villi or amniocentesis is rather painless and safe for today. In doing so, it gives fairly accurate results. A biopsy of a chorion during pregnancy does not harm the fetus. villi, which are taken for the test, disappear with the development of the fetus, this analysis does not create a threat of pregnancy (maximum 1%). The percentage of miscarriages is so small, and the result is so accurate that many women decide to risk and learn about the diagnosis of the fetus as early as possible. And yet, doctors warn of possible complications such as pain, infection, bleeding, abortion, which can occur after a diagnostic
Whether to make a biopsy of a chorion?
Whether to do a chorionic biopsy or not, only a woman can decide, taking into account the advice of the doctor and analyzing the possible risks. Modern medicine makes every effort to exclude the possibility of the birth of a child with developed hereditary diseases and negative chromosomal mutations. Diagnostics and tests that suggest that future mothers in reproductive medicine centers can be allowed to prevent possible deviations in fetal development and ensure the birth of a healthy child.