Metrogil refers to the group of drugs that have antiprotozoal, as well as antibacterial action. Intended for external use.
The drug Metrogil has several forms of release: gel, tablets, ointment, cream. Has a high degree of activity against anaerobic organisms. Effectively fights against strains that cause bacterial vaginosis . To such a drug as Metrogil vaginal, aerobic organisms are absolutely not sensitive.
Act
It consists in restoring the integrity of the 5-nitro group contained in the drug, transport proteins that contain the cells of anaerobic pathogens. The restored nitro group Metrogil vaginal, as indicated by the instruction, begins to interact with the DNA of the causative agent, thereby suppressing the synthesis of nucleic acids, which causes the causative agent to die.
After intravaginal single injection of vaginal cream Metrogil in an amount of 5 g, the maximum level of the drug in the blood of the woman applying it is reached after 7-12 hours.
Bioavailability of the gel form of the drug is higher than that of the tablet, which is achieved by an increased penetrating ability of the drug in the vaginal fluid. That is why the necessary therapeutic effect of using vaginal Metrogil in the form of a gel is achieved at low drug concentrations, which reduces the likelihood of side effects.
Indications
The main indications for the use of the drug vaginal metrogil gel are vaginosis of bacterial etiology, which were confirmed as a result of microbiological diagnosis.
Application
The recommended dose of a single use is 5 g, i.e. 1 whole applicator, which is contained in a box together with a tube of the drug. Apply vaginal gel Metrogil strictly according to the instructions in the box. Place the gel 2 times a day. The recommended time for the procedure is morning and evening.
During treatment, it is recommended to avoid sexual intercourse, which is usually warned by the doctor prescribing the drug.
Side effects
When using the drug occasionally, side effects from some systems appear. So, from the side of the genitourinary system, cervicitis , vaginitis, burning and itching in the vagina, as well as vulva, the appearance of various discharge, and vulvar edema can occur.
On the part of the digestive organs, a woman may experience a metallic taste and, as a consequence, a decrease in appetite, and nausea and vomiting may appear. Often observed and violations of the digestive process, such as diarrhea or constipation.
Many women during the period of using the drug noted the appearance of headaches, dizziness.
Contraindications
The main contraindications for the use of the drug Metrogil vaginal, which are indicated in the instructions, are:
- Hypersensitivity, both to the drug itself as a whole, and to its individual components. To avoid such cases, it is necessary before applying the medication, carefully read the instructions.
- There are allergic reactions to the drug in the woman's history.
Gel vaginal Metrogil with current pregnancy is used only for life indications, after a full assessment of the future benefits for the mother herself, as well as the possible risk of the fetus.
This drug is dispensed only by prescription and should be used solely for its intended purpose.