Chloramphenicol analogues

Chloramphenicol has a broad spectrum of antimicrobial activity and is effective against gram-positive and gram-negative microorganisms. Chloramphenicol, analogues of which are widely distributed in many fields of medicine, are represented by various dosage forms.

Preparations of chloramphenicol

A physician may decide to prescribe to a patient many medications with an identical active substance. Most of the existing substitutes have similar indications, but they differ in the principle of action. The main analogues of the drug, which include chloramphenicol, are:

• Synthomycin;
• Levovinisole;
• Levomycetin .

Levomycitin is available as a solution or paste for external application, as well as in the form of eye drops (Levomycetin Acos) or powder for formulation for injection (Levomycitin succinate).

Also, chloramphenicol has other substitutes and analogues represented by such trade names:

• Levovinisole;
• Levosin;
• Cortomycetin;
• SALESEPT;
• Saladez;
• Veropharm.

It should also be noted anti-inflammatory ointment Levomethyl, in which, in addition to chloramphenicol, there is methyluracil. Often doctors prescribe to the patient just such a combination of substances, indicating it in the recipe, instead of the usual trade name, which often causes confusion.

If the patient is intolerant of the main substance, then he may be prescribed drugs that have a different composition.

The use of chloramphenicol analogues

Preparations containing chloramphenicol are used in the control of infectious diseases, such as:

• brucellosis ;
• meningitis;
• salmonellosis;
• rickettsiosis;
• chlamydia;
• typhoid fever.

Also, these agents are prescribed to suppress the activity of other pathologies, the pathogens of which are sensitive to the components, and in those cases, if other antibiotics were powerless.

Chloramphenicol and its analogs are used according to such instructions for use:

1. Internal reception is carried out half an hour before meals, for adults, the usual dosage is 0.5 grams every six hours, for children this amount is calculated based on body weight and age.
2. For external use, gauze-impregnated tampons are used or simply apply ointment to the affected areas, applying a bandage on top.
3. In eye diseases, chloramphenicol preparations drip two drops up to five times a day. The duration of treatment should not be more than two weeks.