The drug Akatinol Memantine is a medicine in the form of tablets, which is used for dementia - a decrease in mental abilities with memory impairment, thinking, concentration, loss of acquired skills and other abnormalities.
In most cases, this pathology develops gradually and is peculiar to elderly people, but also sometimes occurs in young people and children under the action of factors that cause the death of cells in the cerebral cortex. This can occur as a result of craniocerebral injuries, intoxications, infections, vascular pathologies, etc.
Acatinol Memantine is a patented drug that is produced in Germany by a large pharmaceutical company Merz, which is the developer of this drug for the treatment of dementia. However, today there are many analogs (generics) of Akatin Memantine, produced by other manufacturers, including domestic ones. Here is a list of these drugs, but first we'll look at how these drugs work on the body.
Pharmacological action of Acathinol Memantine
The main active component of the drug Akatinol Memantine, as well as its analogs, is the memantine hydrochloride compound. This substance, absorbed from the gastrointestinal cycle and penetrating into the blood, has the following effects:
- stimulation of the glutamatergic system
- regulation of the transport of ions into neurons;
- improvement of nerve impulse transmission and excitation generation;
- normalization of membrane potential;
- decrease in the intake of ionized calcium in neurons, etc.
As a result, the following therapeutic effect is achieved:
- increase in the degree of brain activity;
- increase of mental abilities;
- improving memory, ability to concentrate;
- decrease fatigue and symptoms of depression;
- reduction of speech disorders;
- increased physical activity;
- reduction spasticity of skeletal muscles.
Taking medications based on memantine allows you to stop the progression of mental disorders, to keep patients' ability to self-service.
List of analogues of Acatinol Memantine:
- Alzheim (Argentina);
- Memantine-TL (Russia);
- Memanine (Russia);
- Mémicar (Russia);
- Memorial (Russia);
- Noogeron (Croatia);
- Abixa (Denmark).
The use of Acatinol Memantine and its analogues
Tablets Akatinol Memantine, as well as substitute drugs, it is recommended to use during meals, washed down with water (no need to chew). The dosage of the drug is individual for each patient. The initial dose, as a rule, is 5 mg per day. After a while, the dosage rises (most often up to 30 mg per day).
It should be borne in mind that drugs based on memantine can be prescribed only by a doctor and should be taken under medical supervision. In addition, for the treatment of dementia, general measures of influence on the body should be applied, including rational nutrition, appropriate physical and mental load, etc.
Contraindications to the use of the analogs of Acatinol Memantine
Acatinol Memantine and its analogs are recommended to be used with caution for treatment in the presence of the following pathologies:
- heart failure;
- thyrotoxicosis ;
- epilepsy;
- myocardial infarction;
- convulsions.
In these cases, the drug may be prescribed for use in lower doses.
Also, remedies based on memantine are not prescribed for:
- pregnancy and lactation;
- expressed violations of kidney function;
- individual intolerance to the components of the drug.