Cardiomagnesium and TromboAss are medicines that belong to the group of non-steroidal anti-inflammatory drugs and anti-aggregates. Both drugs are available in the form of tablets for oral administration. These drugs are interchangeable and are often appointed by specialists to choose from. In this case, patients often have a question: what is the best thing to buy - Cardiomagnum or TromboAss? Let's try to understand, than differs ТромбоАСС from Кардиомагнила, and what is better to get in a drugstore.
Why Cardiomagnum and TromboAAS are analogues?
Both Cardiomagnum and TromboAss have the same indications for use, which include:
- prevention of thrombosis and acute heart failure in the presence of risk factors (advanced age, hyperlipidemia, hypertension, diabetes, obesity);
- prevention of repeated myocardial infarction;
- ischemic stroke;
- unstable angina;
- deterioration of blood supply to the brain and prevention of thrombosis after surgical interventions for the implementation of aortocoronary bypass and coronary angioplasty.
The effect of these drugs is based on the property of acetylsalicylic acid, which is the main active substance of both drugs, to affect certain enzymes. As a result, the synthesis of prostaglandins, prostacyclin and thromboxane is blocked. Acetylsalicylic acid also reduces aggregation of platelets, thereby preventing thrombosis.
The antiaggregant effect of acetylsalicylic acid in the preparations of Cardiomagnesium and TromboACA develops after taking the drug and persists for a week after a single dose. Preparations are quickly absorbed from the gastrointestinal tract and subsequently excreted by the kidneys.
The difference between Cardiomagnet and TromboAss
But, despite the interchangeability and the same indications, the drugs Cardiomagnesium and TromboAss have some differences. First of all, they are determined by the composition of medicines. The cardiomagnet, in addition to acetylsalicylic acid, contains one more active ingredient - magnesium hydroxide.
Magnesium hydroxide in Cardiomagnesium is an antacid and laxative and is formulated to neutralize the harmful effects of acetylsalicylic acid on the gastric mucosa. This substance interacts with gastric juice and hydrochloric acid, and also covers the walls of the stomach with a kind of protective film.
Thrombose AAC from active substances contains only acetylsalicylic acid. But the tablets themselves are covered with a special intestine-soluble protective coating, resistant to the action of hydrochloric acid in the stomach and dissolving in the duodenum. Thus, minimization of the negative effect of acetylsalicylic acid on the stomach is also achieved.
Also, the preparations in question are available in various dosages relative to the content of acetylsalicylic acid. Thus, a cardiomagnet can contain 75 or 150 mg of the main active substance in one tablet, and TromboAcc 50 or 100 mg. The necessary dosage is selected by the doctor individually depending on the form and stage of the disease.
Cardiomagnesium and TromboAss - side effects
Basically, both drugs are well tolerated by patients. But in some cases, the following adverse reactions may occur:
- urticaria, Quincke's edema , anaphylactic reactions;
- nausea, vomiting, abdominal pain, ulcers of the mucous membrane of the stomach and duodenum;
- bronchospasm;
- dizziness, drowsiness, insomnia;
- increased bleeding, anemia, thrombocytopenia, and others.