Often, women suffering from attacks of acute headache, take analgesics , which only aggravate the condition, and eventually cease to help. Triptans from migraine are really effective - drugs designed specifically to treat this disease. They not only quickly relieve the pain syndrome, but also prevent the development of an attack, if you take medications with the very first symptoms of the pathology.
How do drugs from the triptane group work?
The main mechanism of work of this type of drugs is to stimulate the receptors of the vascular walls. Moreover, tryptans produce a selective effect and act exclusively within the dura mater, without affecting the coronary and peripheral circulatory system. As a result, excessively dilated blood vessels narrow, which contributes to an instant decrease in the severity of the pain syndrome.
In addition, the described drugs reduce the sensitivity of the trigeminal nerve receptors at the level of the spinal nucleus. Due to this pain is almost not felt.
In addition to the immediate management of migraine symptoms, including nausea, light and noise, dizziness, medications of this group are used for preventive purposes. They effectively reduce neurogenic inflammation and prevent pulsation in the blood vessels.
Triptans have several advantages over conventional analgesics:
- cause fewer side effects;
- Do not provoke addiction and the need to increase dosage;
- work in any phase of the attack;
- prevent the progression of pain, if you take the pill at the first symptoms;
- relieve signs of aura;
- struggle with concomitant clinical manifestations of the disease.
What drugs are related to triptans?
The drugs in question are selective 5HT18 / D receptor antagonists. They are chemical derivatives of 5-hydroxytryptamine, which is required by name.
There are two generations of drugs containing triptans. The first includes all medicines based on sumatriptan - the very first and thoroughly studied representative of the group. The second generation includes medicines with the following ingredients:
- zolmitriptan;
- eletriptan;
- naratriptan;
- almotriptan;
- rhizotriptan;
- lt; / RTI & gt;
New drugs have a more pronounced clinical effect and improved pharmacological properties. They help faster and cause fewer side effects.
It is worth noting that almo-, rhizo- and fluorotriptans are still undergoing medical tests and are undergoing research, so they are not yet available for free.
List of drugs from migraine from the group of triptans
To pick up to itself medicines for a headache it is better under the reference of the doctor. Despite the same mechanism of action of triptans, each patient is helped by one kind of medication, which will help select a specialist after a careful study of the individual characteristics of the patient and anamnesis.
List of drugs:
1. Sumatriptans:
- Rapimed;
- Imigran;
- Sumatriptan;
- Trimigrene;
- Amigrenin;
- Sumygamren.
2. Zolmitriptans:
- Zomig.
3. Eletriptans:
- Relpaks.
4. Naratriptans:
- Naramig.
Approximately half of people suffering from migraine attacks have a headache return within 2 days even with the described medications. Therefore, at least 2 hours after taking the tryptane, it is advisable to take another tablet of the drug. It is important not to exceed the recommended dosage.