The analysis of Rarr-A (Papp-A) in pregnancy - what is the essence?
A characteristic marker of the risk of childbearing with some problems at the gene level is the level of Rarr-A in pregnancy, or more accurately - its compliance with the norm. If you literally decipher and translate from English this abbreviation, then Rarr-A is nothing more than a pregnancy-associated protein A-plasma, the concentration of which increases in proportion to the time.
Doctors recommend to undergo examination from 8 to 14 weeks of pregnancy. But, since the RARR-A is determined in conjunction with HCG, the optimal time to take the RARR-A test for pregnancy is the interval from 11 to 13 weeks. At this stage, the results will be as informative as possible.
Because Rapp-A can indicate chromosomal abnormalities of the fetus, a double test is strongly recommended to pass through to women:
- over the age of 35;
- already having children with similar problems;
- having relatives with genetic disorders;
- shortly before pregnancy, rubella, hepatitis, herpes or cytomegalovirus ;
- with complicated or interrupted pregnancies in the early period, in the past.
If Rarr-A during pregnancy does not meet the norm, the doctor will prescribe an additional examination in order to make sure that everything is fine with the baby.
The unit of measure is RARR-A-mU / mL, and the limits of the norm depend on the gestational age, thus:
- 0,17-1,54 the range of permissible values for a period of 8-9 weeks;
- 0.32-2.2-9.10;
- 0.46-3.73-10.11;
- 0.79-4.76-11.12;
- 1.03-6.01 - 12-13.
Reduced and elevated RARP-A (Papp-A) in pregnancy
If the Rahr-A during pregnancy is raised, then most likely, there was an error in determining the duration of pregnancy. Therefore, experts recommend, before doing a screening, first to undergo ultrasound, in order to determine the exact period of gestation. At the same time, the increased value does not exclude the possibility of pathological abnormalities.