Exselon plaster is used to treat dementia - serious intellectual and behavioral disorders of a person. This drug, which can significantly improve the quality of life of people who have lost basic skills in everyday life.
Pharmacological action of the plaster Exelon
Exelon plaster is a medicine of a group of selective inhibitors of acetyl- and butyrylcholinesterases of the brain. The main active substance of this drug is rivastigmine. The patch has a round shape, the diameter of which is several centimeters. The amount of rivastigmine that is released within 24 hours after you secured the Excelon patch is 4.6 mg.
This drug has an excellent anticholinesterase pharmacological effect. After its application:
- slowing down the destruction of acetylcholine, which is produced by neurons that have retained their functionality;
- the amount of acetylcholine in the cerebral cortex increases;
- slows the formation of various fragments of the protein precursor of beta-amyloid, which avoids the formation of amyloid plaques.
According to the instructions for use, the Ekselon patch is used to treat Alzheimer's disease . It can be used at any stage of the development of this disease. Regular gluing of the patch leads to improvement of various cognitive functions (speech, attention, memory), as well as to a rapid decrease in the severity of all behavioral and mental manifestations of the disease (agitation, tearfulness, hallucinations). Thanks to this patient for many years can lead a normal and active lifestyle.
How to use the plaster of Exelon?
The instructions say that the Excelon patch should only be used once a day. Neglect this rule is strictly prohibited. If the patient has a good tolerance of the drug, after about 4 weeks of treatment, the dose may be slightly increased. In this case, the Excelon patch with 4.6 mg of rivastigmine is replaced with the same patch with 9.5 mg of the active ingredient. The therapy was interrupted for a couple of days? It is necessary to begin treatment anew with a plaster with a minimum content of rivastigmine.
Glue it only on absolutely dry and undamaged skin. It is best in the upper back or on the lower back, on the shoulder or on other sites with a minimal hairline and where it will not come into contact with clothing. Patients should not use creams, lotions, powder, oils, as well as other cosmetic products for the skin, as this will lead to the peeling off of the patch.
Taking a bath or showering procedures absolutely does not affect the fixation of this plaster. It can be worn under bathing clothes. Do not use such a tool to treat Alzheimer's disease under direct UV rays.
The plaster should be replaced with a new one after exactly 24 hours. Before replacing, you must first take off the used Exelon and only then paste a new one. It is recommended to constantly alternate places for application. The patient is not allowed to use the same site for sticking the patch for several days.
Contraindications to the use of the plaster Exelon
Plaster Exelon - a drug that has contraindications, so it must be applied very carefully. It can not be used when:
- increased sensitivity of the patient to rivastigmine;
- sinoatrial blockade or AV-blockade;
- expressed violations of any liver function.
Plaster Exelon and its analogues (Rivastigmine and Alzenorm) should be used with caution in patients with severe bronchial asthma or various obstructive airway diseases.