Hyperfunction of the ovaries

Hyperfunction of the ovaries is a very rare phenomenon, in contrast to hypofunction, and is observed only in 10-15% of women. In this case, this phenomenon is usually characterized as hyperadromia or hyperestrogenia.

Hyperadromia is the physiological state of the female body, in which increased production of androgens is observed. When hyperestrogenic - increases the concentration of estrogens in the blood.

What can cause ovarian hyperfunction?

The reasons that cause the development of this condition are the following:

1. Excess of the hormone insulin in the body. It is this hormone that activates the synthesis of the luteotropic hormone, and then androgens in the ovaries and adrenal glands.
2. The presence of tumor-like ovarian formations, which can also synthesize an excess of androgens. So, for example, Leydig cells, called lezdigoms, synthesize the hormone testosterone.
3. Enzymatic insufficiency. For example, a deficiency in the body of 3p-hydroxysteroid dehydrogenase leads to an excess of dehydroepiandrosterone.

How is ovarian hyperfunction manifested?

Symptoms of hyperfunction of the ovaries are most often hidden, which prevents you from starting treatment at the right time. Most often, women complain of irregular menstruation, as well as menorrhagia, which is caused by a prolonged increase in the level of estrogens in the blood, which in turn disrupts the periodic fluctuations in the content of progesterone.

However, in most cases, the woman learns about the hyperfunction of the ovaries only after carrying out laboratory tests. So in blood and urine the level of androgens rises. In this case, the body of a woman begins to acquire masculine traits: muscle mass increases, hypertrichosis is observed .

The consequence of this disorder is ovarian hypertrophy. This phenomenon manifests itself, first of all, in increasing their size, which is confirmed by the results of ultrasound.