In some cases, after performing the procedure of in vitro fertilization, doctors themselves make an incision of this shell, thereby helping the embryo to gain a foothold in the uterine cavity. According to most experts involved in IVF procedure, this process often contributes to the onset of pregnancy. Such manipulation is called "auxiliary hatching of embryos".
How is this kind of manipulation carried out?
Having dealt with the fact that this is hatching in the program of ECO, let's briefly describe the peculiarities of this manipulation.
As a rule, it is prescribed in those cases when the previous attempts to become pregnant with the help of in vitro fertilization in women ended unsuccessfully.
In itself, manipulation refers to the category of microprocedures and is conducted under a microscope with a large increase. When it is carried out in the area of the pellucida, the doctor makes an incision, and only after that, the embryo is introduced directly into the uterine cavity. That is, in other words, - doctors specially make an artificial hole to help him gain a foothold in the wall of the uterus.
Specialists in the field of IVF argue that this kind of procedure dramatically increases the chances of pregnancy in women after 35 years, and also helps those women who have infertility with etiology, not fully studied.
In what cases can laser hatching of embryos be given in IVF?
In view of the fact that the incision made during this manipulation is measured by several nanometers, it is carried out using a special laser, hence the name of the procedure.
On various Internet portals, you can find reviews of potential moms that hatching is a useless thing and an extra waste of money. the effect of such a procedure is zero. In fact, this is not so. Studies conducted by Western specialists in IVF confirmed that the incision of the pellucida allows to increase the probability of implantation by more than 50%. However, it is also necessary to take into account the fact that even if hatching is carried out, this can not guarantee that the embryo embryo landing at ECO will always be successful.
The thing is that the implantation process is rather complicated, from a biological point of view. And even if the incision of the outer envelope of the embryo has been carried out, this is not yet a guarantee that fixing it in the endometrium of the uterus will be successful.
In order to increase the chances of pregnancy, doctors recommend a hatching procedure in the following cases:
- the woman's age is more than 35 years;
- elevated blood levels of follicle-stimulating hormone;
- incorrect type and percentage of blastomere fragmentation during embryogenesis;
- large thickness of the zone of the pellucida in the embryo (more than 18 nm).
This procedure is mandatory when the blastomer indicator is exceeded by 10% or more, and in the presence of an embryo, the number of blastomeres is less than 6.
Auxiliary hatching is contraindicated in cases where the embryo blastomeres are not in the interphase of meiosis 1.
Thus, as can be seen from the article, hatching is a very important manipulation in the process of in vitro fertilization, helping at times to increase the chances of implanting the embryo in the uterine endometrium and contributing to the onset of pregnancy.