Many people need a constant intake of any medications to correct existing diseases or prevent complications with existing disorders of the functioning of the body. One of these medicines is the Cardiomagnesium tablets, the benefit and harm of which should be evaluated individually for each patient.
Cardiomagnum - composition
This tablet preparation belongs to the pharmacotherapeutic group of antithrombotic agents. The medicine is produced by the company Nicomed, packed in glass jars of 30 or 100 tablets, each of which has the shape of a heart or an oval, depending on the dosage. Tablets of white color, covered with a thin film shell, have a notch. Interestingly, the active substance of the drug is acetylsalicylic acid - the basis of all known Aspirin, often used as an anesthetic and antipyretic.
Dosage of acetylsalicylic acid in the drug Cardiomagnesium - 75 mg and 150 mg in each tablet, which is a daily rate. It is worth noting that to achieve anesthesia, reduce inflammation and body temperature requires the intake of more of this compound (300-1000 mg). In addition, the active ingredient Magnesium hydroxide is included in the Cardiomagnesium, which can be contained in an amount of 15.2 or 30.39 mg in each tablet. The auxiliary components of the medicine are:
- starch;
- talc;
- cellulose;
- magnesium stearate;
- propylene glycol and the like.
Action Cardiomagnola
Due to the content of acetylsalicylic acid in the above dosages, the drug Cardiomagnesium has an antiaggregant effect, i.e. prevents the aggregation of platelets. These elementary blood particles are able to connect to each other, providing blood clotting, which is necessary to stop bleeding when the vessels are damaged. In the case of some disorders, hyperaggregation is observed - excessive clotting of platelets, which leads to the formation of blood clots , clogging of blood vessels and disruption of blood supply.
The mechanism of action of the drug is associated with the ability of acetylsalicylic acid to inhibit the activity of the enzyme cyclooxygenase (COX-1), resulting in a blockage in the platelets synthesis of thromboxane A2, a mediator of aggregation of these blood particles. This is the suppression of the adhesion of platelets, blood clots. It is assumed that the active substance Cardiomagnola suppresses this process by means of other mechanisms, which have not yet been fully studied.
As for the second important component of the tablets considered, magnesium hydroxide, its inclusion in the preparation is carried out in order to protect the walls of the gastrointestinal tract from the irritating effect of acetylsalicylic acid on them. Protective action is achieved by forming a film on the mucous tissues of the stomach, which prevents contact with acids. In this case, both substances, both antiplatelet and protective, do not interfere with each other, providing a quick and effective action.
Cardiomagnet - benefit
Tablet drug Cardiomagnolo, the benefit and harm of which is well studied due to numerous studies and clinical trials, is a vital preparation for patients with increased tendency to thrombosis. Due to the regular intake of this medicine, the risk of developing serious cardiovascular diseases is reduced. Tablets Cardiomagnesium can prolong life and improve the prognosis even with severe diagnoses.
Cardiomagnet - indications for use
Recommendations for the use of this drug are associated with the prevention of thrombosis and the development of cardiovascular ailments and people at increased risk of such diseases, as well as the recurrence of already occurred episodes of pathologies associated with hyperaggregation of platelets. Let's list, for what often prescribe Cardiomagnet, indications for its application:
- a stroke or myocardial infarction caused by clogging of blood vessels with a thrombus;
- stable arterial hypertension;
- obesity;
- diabetes;
- excess in the blood of cholesterol ;
- acute or chronic ischemic heart disease;
- hereditary predisposition to cardiovascular diseases;
- migraine, accompanied by stagnation of blood in the vessels;
- postoperative prophylaxis of thromboembolism after surgical interventions on the coronary arteries and heart valves;
- old age.
Cardiomagnet - harm
Knowing about the negative effect of acetylsalicylic acid on the walls of the stomach, many patients think about whether it is possible to take Cardiomagnesium in diseases of the digestive system. The main active substance of these tablets causes dyspeptic disorders and erosive-ulcerative lesions of gastric tissues, but in combination with magnesium hydroxide negative effects are minimized. Evaluating the benefits and harms of the drug Cardiomagnesium, we can say that with the threat of thrombosis, the therapeutic effect significantly exceeds possible side effects.
Cardiomagnet - side effects
In addition to the effects on the stomach, accompanied by heartburn, abdominal pain, the development of gastric erosion and bleeding, the effect of the main component of the Cardiomagnesium tablets can also be caused by side effects associated with other organs and systems. Consider what is included in the list of the most common adverse reactions associated with treatment with this drug:
- bleeding from the organs of the genitourinary system;
- nasal bleeding;
- bleeding gums;
- anemia;
- kidney failure;
- asthmatic conditions;
- skin rash and itching;
- nasal congestion;
- angioedema;
- cardiopulmonary insufficiency;
- tinnitus;
- loss of consciousness;
- headache;
- dizziness;
- insomnia.
Cardiomagnesium - contraindications
Reception of the Cardiomagnet should be canceled, replacing it with a drug with a similar effect, if there are the following factors:
- intolerance to salicylates, acetylsalicylic acid, other ingredients of the drug;
- asthma associated with the use of salicylates or other non-steroidal anti-inflammatory drugs;
- severe renal failure;
- severe heart failure;
- serious impairment of liver function;
- increased tendency to bleeding (with vitamin K deficiency, thrombocytopenia, hemorrhagic diathesis);
- exacerbation of peptic ulcer of the stomach and duodenum;
- the first and third trimesters of bearing the fetus;
- age to 18 years;
- deficiency of glucose-6-phosphate dehydrogenase.
For patients under 55 years of age, a prolonged intake of the drug for prophylactic purposes, taking into account the risk of thrombosis, is prescribed with extreme caution. In addition, with the appointment of Cardiomagnesium, the parallel use of certain medications should be excluded, among which: other types of antiplatelet agents, anticoagulants, Ibuprofen, Methotrexate, ATP inhibitors, Acetazolamide, Furosemide, alcohol-containing agents,
How to take a cardiomagnet?
The drug can be taken only on the prescription of a doctor who, knowing the medical history, after carrying out the necessary diagnostic measures, will be able to determine what benefits and harms from the drug Cardiomagnesium are expected. He will prescribe a dosage and tell you how to drink Cardiomagne correctly to achieve the most positive result of treatment. Often, cardiomagnesium (75 mg or 150 mg) is taken once a day. Tablets should be washed down with a sufficient amount of water.
Cardiomagnet for prevention
The drug Cardiomagnet, the use of which is recommended for preventive purposes to prevent the formation of blood clots, shows an effect with minimal dosages obtained regularly. It is best to drink these tablets at the same time, strictly every 24 hours. The duration of the course can be different, depending on the pathology and tolerability of the medication, sometimes a life-long reception of the Cardiomagnola is prescribed.
Cardiomagnet in pregnancy
In view of the toxic effect of acetylsalicylic acid on the fetus, which threatens with various developmental defects, especially in the first three months of pregnancy, Cardiomagnesium is not prescribed a drug during this period. In the last trimester, these pills, in addition to negatively affecting the unborn child, can negatively affect delivery, provoke bleeding. When carrying a baby in special, vitally necessary cases, the Cardiomagnet can be administered only in the second trimester, subject to the minimum doses and a short course of admission.
Cardiomagnet analogues
On the basis of acetylsalicylic acid, other antithrombotic drugs are produced, which it is possible to replace the tablets under consideration. It should be noted that it is better than Cardiomagnola, according to medical studies and patients' reviews, no medicine is being produced yet. Thanks to the inclusion of a protective ingredient that does not allow damage to the stomach, these tablets outperform even those that are covered with a special enteric coating.
Analogues of the Cardiomagnet containing acetylsalicylic acid include:
- Aspirin Cardio ;
- Trombo ACC ;
- Acercar;
- Aspicor.