The substance dexpanthenol is a derivative of pantothenate, water-soluble provitamin B5, widely used in medicine in a variety of different preparations, both local and systemic. Most often, for therapeutic purposes, it is used dexpanthenol in the form of an ointment, as well as cream and gel. Let us discuss in more detail precisely on some of these dosage forms, we will consider what are the features of their use, and how these drugs work.
Application of ointment Dexpanthenol
Ointment Dexpanthenol (analogues - Bepanten, D-panthenol, Pantoderm) is an external drug that is prescribed in the following cases:
- burns (thermal, solar, etc.);
- aseptic postoperative wounds;
- dermatitis;
- furuncles;
- abscesses;
- pressure sores ;
- cracks in the nipples;
- cuts;
- abrasions;
- excessive dryness of the skin;
- pathology of the mucous membrane of the throat of the uterus, etc.
In the formulation of the dexpanthenol ointment, in addition to the main active substance (dexpanthenol), there are substances such as:
- petrolatum;
- cholesterol;
- Vaseline oil;
- isopropyl myristate;
- methylparahydroxybenzoate;
- propyl parahydroxybenzoate;
- prepared water.
The drug, penetrating well into all layers of the skin, contributes to the improvement of trophism and the rapid regeneration of tissues. Dexpanthenol actively participates in metabolic processes, has an intensive effect on the function and formation of epithelial tissue, accelerates healing processes. It also produces a slight anti-inflammatory effect and increases the strength of collagen fibers.
According to the instructions for use, ointment Dexpanthenol is usually applied to the affected areas twice - four times a day with a thin layer. Before applying to the area of infected wounds, any antiseptic should be pre-treated.
Ointment (cream) Dexpanthenol E
Another drug, often recommended for use in various skin inflammations and lesions, is Dexpanthenol cream with vitamin E. The combination of dexpanthenol and vitamin E (tocopherol) enhances the regenerative properties of the drug. In addition, the use of this agent helps maintain a normal water-lipid balance of the skin, smoothing the scars, has a mild soothing effect.
Dexpanthenol with vitamin E has the same indications for use as dexpanthenol ointment. Also, this cream is recommended for preventive maintenance of healthy skin, especially with negative meteorological influences (strong wind, frost, intense sun radiation).
Eye ointment with dexpanthenol
Dexpanthenol is also introduced into drugs used in ophthalmic practice. One such remedy is the eye gel Korneregel. In addition to dexpanthenol, this preparation contains the following excipients:
- cetrimide;
- disodium edetate;
- sodium hydroxide;
- carbomer;
- purified water.
Dexpanthenol for the eyes is prescribed in such cases:
- eye burns;
- dystrophic diseases of the cornea;
- keratitis of various etiologies;
- postoperative defects of the cornea;
- corneal conjunctival xerosis;
- erosion of the cornea of the eye.
Also, the drug is recommended to use people wearing contact lenses to prevent damage to the cornea. Stimulating the processes of renewal, participating in the metabolism and removing inflammation, the drug helps to quickly repair the damaged cornea.
The drug is convenient to use, the standard dosage is 1-2 drops daily in the affected eye. When the eyelids are closed, the gel is transformed into a liquid phase, which corresponds to the physiological parameters of the lacrimal fluid. Korneregel is permanently retained on the surface of the cornea. does not penetrate deep into the eye tissues.