Many infectious diseases, especially those threatening with severe complications, are treated with the use of systemic antibiotics. There are a large number of different types of antibiotics classified into groups that have a different chemical structure and have different effects on the human body and microbes. Consider to which group of antibiotics the Clacid drug belongs, under what diseases it is recommended and which has contraindications.
Composition, Forms and Properties of the Antibiotic Clacid
The main substance of Clacid is the semisynthetic compound clarithromycin, which belongs to the antibiotic group of macrolides. This group of broad-spectrum antibiotic drugs is considered one of the least toxic. In addition, Clacid is one of the safest antibiotics because it does not suppress the human immune system, as occurs with many other antimicrobial drugs.
The substance clarithromycin penetrates into the human body quickly penetrates into the affected tissues and cells and provides high tissue concentrations. In addition, this antibiotic is able to penetrate into the bacterial cell, as well as inside the cells of the body. This is important in the treatment of diseases caused by intracellular pathogens. At the same time, sufficiently high concentrations of the drug within the cells are noted, which persist for the optimal time.
In addition to the antimicrobial action, which consists in suppressing protein synthesis in a microbial cell, Clacid exhibits anti-inflammatory and immunomodulatory properties.
The main forms of the release of Clacid are:
- powder for solution for intravenous infections;
- oral tablets in the shell.
The drug is active against the following microorganisms:
- Gram-positive bacteria (staphylococci, streptococci, listeria, etc.);
- Gram-negative bacteria (hemophilic rod, gonococci, Legionella, Pasteurella, Helicobacter pylori, Campylobacteria, Branhamella, Pertussis stick, etc.);
- anaerobic microorganisms (bacteroids fragilis, clostridia, peptococci, peptostreptococci, propneobacteria acne, etc.);
- other microorganisms (chlamydia, mycoplasma, ureaplasma, borrelia, mycobacteria, etc.).
The enterobacteria, Pseudomonas aeruginosa, and other gram-negative microorganisms that do not decompose lactose are not sensitive to this antibiotic.
Indications for use of the drug Klacid
Most often, the antibiotic Klatsid is prescribed for respiratory tract infections (bronchitis, pneumonia, pharyngitis, laryngitis, sinusitis, etc.). It can also be used in the treatment of infections of the ENT organs and odontogenic infections (otitis media, pulpitis, periodontitis, etc.). Other indications of the drug are:
- peptic ulcer;
- sexually transmitted infections;
- infections of soft tissues, skin (erysipelas, folliculitis, etc.), etc.
Method of application of the drug Clacid
According to the instructions for use, the antibiotic Clacid should be taken without chewing, regardless of food intake. The standard dosage is 250 mg twice a day. The duration of treatment is 5-14 days. In some cases, treatment with the drug is combined with the intake of antibiotics from other groups.
Contraindications to the admission of Clatida:
- serious violations of the liver and kidneys;
- porphyrin disease;
- pregnancy, lactation;
- a special sensitivity to the drugs of the macrolide group.
It is forbidden to combine treatment with the use of certain medications, among which:
- Astemizole;
- Pimozide;
- Cisapride;
- Terfenadine.