Since inflammation of the pelvic organs is caused by polymicrobial infections, one of the mandatory components of their treatment are antimicrobial drugs, which have high activity in the fight against anaerobes and pathogens of protozoal infections, among which the special place is occupied by Metronidazole.
This tool has been widely used, both in the treatment of diseases of the lower parts of the female reproductive system, and in the treatment of septic conditions in gynecology and obstetric practice.
This tool is used in various forms. It can be tablets and cream, and vaginal suppositories, and vaginal gel, and injection.
Metronidazole has a high degree of bioavailability; therefore, contraindications for its use in obstetrics and gynecology are allergic reactions to this agent, organic lesions of the central nervous system, the period of pregnancy and feeding the baby with breast milk, abnormalities in liver function, blood diseases.
Indications for use of metronidazole in gynecology
Local use of the drug, that is, in the form of vaginal suppositories with metronidazole or vaginal gel, is indicated in the treatment of trichomoniasis, thrush, bacterial vaginosis , urethritis.
If the urogenital infection recurs constantly, and also in the case of trichomoniasis, the doctor necessarily complements the local therapy with metronidazole by its systemic use in tableted or injectable forms.
How does Metronidazole apply?
- Tablets of the drug are usually applied three to four times a day for 250-750 mg.
- Intravenously, the drug is administered every eight hours for 500-750 mg.
- Candles are administered intravaginally once a day for 500 mg.
How long should be the course of application of the drug, the doctor determines, depending on the severity and nature of the disease. When treating trichomonadic vaginitis with metronidazole, a woman should not have sex. In this case, the course of therapy should also pass and her sexual partner.
When using Metronidazole drugs, patients should refrain from drinking alcoholic beverages, as this can lead to body reactions such as headache, nausea, vomiting, and abdominal cramping.
Side effects of Metronidazole
When starting treatment with metronidazole, as with any other remedy, it must be remembered that it can have side effects. In this case, they are expressed in:
- irritability, headache,
insomnia, depression, dizziness, weakness, ataxia, increased level of excitability, confusion, convulsions, peripheral neuropathy, hallucinations; - allergic reactions in the form of rashes on the skin, hives, itching;
- loss of appetite, taste of metal in the mouth, nausea and vomiting;
- leukopenia;
- irritation in places of topical application of the remedy;
- burning in the urethra ;
- arthralgia.