Leukocytes are of two types: granulocyte and agranulocyte. The first line includes granulocytes in the form of eosinophils, neutrophils and basophils. Neutrophils, in turn, are divided into mature or segment-nucleated, not fully ripe or stab, and immature granulocytes (young). Because of the short duration of this type of leukocytes, about 3 days, they almost immediately ripen.
What is "immature granulocytes" in the blood test?
In the form with the results of a laboratory study of a biological fluid, the number of incompletely ripened and young granulocytes is not indicated, since it is not counted during the analysis. Only the total concentration of segmented and stab neutrophils is indicated.
To calculate the value of IG (the amount of granulocytes), you need to subtract the sum of monocytes and lymphocytes from the total white blood cell count.
The number of immature granulocytes is normal
In an adult, the maturation process of neutrophils occurs quickly, within 72 hours, so their volume in the blood is small. The norm for stab and young granulocytes is up to 5% of the total number of all white blood cells (leukocytes).
Why are immature granulocytes reduced or elevated?
In fact, in a healthy adult, the considered group of neutrophils should not be detected. Therefore, in medicine there is no such thing as "lowering of immature granulocytes".
Pathology is considered if the number of these cells is higher than the established norms. The reasons for this can be pregnancy, intense physical activity, abundant food intake, stress. Also, the concentration of young neutrophils increases with the following diseases and conditions:
- osteomyelitis;
- purulent abscess;
- pneumonia;
- meningitis;
- phlegmon ;
- peritonitis;
- severe burns;
- sepsis;
- inflammation of the appendix;
- purulent sore throat;
- infectious hepatitis;
- cholera;
- otitis;
- psoriasis;
- typhoid fever;
- pyelonephritis;
- scarlet fever;
- gout;
- thrombophlebitis;
- malaria;
- cholecystitis;
- measles;
- some types of dermatitis;
- tuberculosis;
- acute bleeding;
- flu;
- diabetic acidosis;
- rubella;
- lead poisoning;
- Cushing's syndrome ;
- malignant tumors;
- uremia;
- gangrene;
- serum sickness;
- myocardial infarction;
- bites of poisonous insects;
- chronic myeloplastic pathologies;
- lung infarction;
- taking drugs of lithium, androgens, glucocorticosteroid hormones.