From the headache, which affects mostly women, Ascofen P is often used in the form of tablets. This drug is a complex agent with a combined composition, including antipyretic and anti-inflammatory components, so it can be used not only for migraines. It is important to know all the features and the exact list of pathologies in which Ascofen P is prescribed - from what these tablets, how they affect the cardiovascular system, what are their main side effects and signs of overdose.
The complete composition of the drug Askofen P
The active ingredients of the drug:
- paracetamol;
- Acetylsalicylic acid (aspirin);
- caffeine.
Tablet excipients:
- low molecular weight medical povidone;
- calcium stearate;
- potato starch;
- stearic acid;
- Vaseline oil;
- talc;
- silicone emulsion.
What helps Ascofen P?
Due to the described combined composition, the presented drug can be attributed to a group of analgesics and antipyretics. Paracetamol has a direct effect on the center of thermal regulation in the hypothalamus. It is also able to weakly inhibit the production of prostaglandins in peripheral tissues. This causes a pronounced antipyretic and obvious analgesic effect in combination with some anti-inflammatory action.
Acetylsalicylic acid is known for its blood thinning properties, aspirin moderately oppresses the intensity of platelet aggregation and, accordingly, the formation of thrombi in the blood vessels. Moreover, this ingredient improves local microcirculation of the biological fluid. Due to this, acetylsalicylic acid produces a noticeable antipyretic, anti-inflammatory effect, is able to arrest pain syndrome.
Caffeine has the following effects:
- increased reflex excitability of the spinal cord;
- expansion of blood vessels in the skeletal muscle region;
- excitation of vasomotor and respiratory centers;
- improving physical and mental activity, working capacity;
- an increase in the diameter of the blood vessels of the kidneys, heart and brain;
- a decrease in the feeling of fatigue, drowsiness;
- reduction of platelet aggregation in the blood.
Tablets of Ascofen II contain only 40 mg of caffeine. This dosage is optimal, since it allows to achieve all of the above effects without significant stimulation of the central nervous system, and also provides normalization of the tone of the cerebral blood vessels and acceleration of the total blood flow in the body.
These pharmacological properties of the active components of the drug cause the testimony to Ascofen P:
1. Feverish syndrome:
- acute respiratory infections;
- flu;
- heat of different origin.
2. Pain syndrome:
- myalgia ;
- headache;
- neuralgia;
- lumbago;
- migraine;
- algodismenorea;
- toothache;
- arthralgia;
- thoracic radicular syndrome .
It is worth noting that this drug helps only from mild and moderate pain.
Increases or lowers the pressure of Ascofen P?
Given the composition of tablets in which caffeine is present, Ascofen P should not be taken by patients with hypertension. The fact that this drug is still able to slightly increase blood pressure.
How dangerous is an overdose of Ascoffen II?
Excess of the doses indicated in the instruction is fraught with an intoxication of the body with acetylsalicylic acid. This is manifested as follows:
- collapse;
- nausea and vomiting;
- convulsions;
- gastralgia;
- bronchospasm;
- anuria;
- the discovery of internal bleeding;
- suffocation;
- respiratory paralysis;
- respiratory acidosis;
- respiratory alkalosis;
- confusion, confusion.