Kombilipen is a preparation of domestic production, which is a complex of vitamins and is produced in two forms - a solution for intramuscular injection (Combinolone for injections) and tablets (Combibilen Tabs). Let us consider in more detail the specific features of the injection form of this drug.
Combipin composition for injections
The preparation in question has a multicomponent composition comprising the following active substances:
- Thiamine (thiamine hydrochloride, vitamin B1) is a substance that plays a significant role in the metabolism of fats and carbohydrates, and also participates in the spread of nerve impulses and supports the normal functioning of the heart.
- Pyridoxine hydrochloride (vitamin B6) is a compound necessary for the normal course of the exchange of proteins, fats and carbohydrates, for the provision of hematopoiesis, the work of the central and peripheral nervous system.
- Cyanocobalamin (vitamin B12) - a biologically active substance, which is necessary for the normal course of hematopoiesis processes and the growth of epithelial cells; It also participates in the production of nucleotides, myelin and the metabolism of folic acid.
- Lidocaine hydrochloride is a local anesthetic and a substance that promotes vasodilation and vitamins digestion.
As additional components in the formulation of the following substances:
- benzyl alcohol;
- sodium phosphate;
- sodium tripolyphosphate;
- sodium hydroxide;
- potassium hexacyanoferrate;
- prepared water for injection.
Kombilipen for injection is issued in ampoules and has the form of a liquid of reddish-pink color with a characteristic odor.
Indications for the use of injections Kublipen
The drug is prescribed as one of the means of therapy in the following pathologies:
- neuralgia of the trigeminal nerve ;
- neuritis of the facial nerve;
- pathologies of the spine, accompanied by painful sensations (intercostal neuralgia, lumbago, sciatica, cervical syndrome, lumbar syndrome, radicular syndrome, associated with the destruction of the vertebrae);
- polyneuropathy of various origins (including diabetic and alcoholic).
Dosage regimen Kombilipen
In most cases, it is recommended to begin the treatment course with intramuscular injection of the drug daily for 2 ml for 5-10 days. In the future, it is possible to switch to the use of the oral form of Kombilipen or the administration of the drug twice or thrice a week for 14 to 21 days. A combination of the two forms of the drug is possible while continuing treatment.
How to prick Kombilipen?
Due to the content of lidocaine, the injections of Kombilipen are not very painful. Often, intramuscular drugs are injected into the upper outer quarter of the buttocks. In the event that it is necessary to put the injection yourself, it is allowed to inject the medicine into the outer upper part of the thigh.
Side effects of Kombilipen
As a result of the use of this drug, the appearance of such undesirable reactions as:
- increased sweating;
- allergic manifestations (itchy skin, Quincke's edema, urticaria, anaphylactic shock, etc.);
- acne ;
- increased heart rate.
Contraindications to the appointment of Kombilipen
Drug for injections Kombilipen is not recommended in the following cases:
- Decompensated heart failure (in severe or acute form);
- hypersensitivity to the components of the solution;
- During pregnancy and breastfeeding.
Cobelipen injections and alcohol
Due to the fact that alcohol significantly reduces the absorption of vitamins, drinking alcohol during treatment with Kombilipen is not recommended.