Cinnarizine is a medicinal preparation of synthetic origin, which is released in the form of tablets. It belongs to the pharmacological group of calcium channel blockers and has been used in medical practice for a long time. Consider how this medicine works, what are the indications for the use of Cinnarizine and its contraindications.
Composition and therapeutic effect of Cinnarizine
The active component of the drug is a substance with the same name - cinnarizine. Auxiliary components in tablets:
- starch;
- milk sugar;
- magnesium stearate;
- polyvinylpyrrolidone K 25;
- aerosil 200;
- cellulose.
The drug has the following effect when ingested:
- improvement of cerebral, peripheral and coronary circulation;
- decrease in the tone of the smooth muscle arterioles;
- suppression of calcium ions in cells;
- antihistamine action;
- a decrease in the excitability of the vestibular apparatus;
- a decrease in the tone of the sympathetic nervous system;
- Reduction of excessive viscosity of blood;
- increasing the resistance of tissues to oxygen starvation;
- vasodilator action (especially cerebral vessels), which has virtually no effect on blood pressure;
- reduction of vascular response to adrenaline, dopamine, norepinephrine, vasopressin.
Indications for the use of tablets Cinnarizine
The main indications for the use of Cinnarizine are:
- circulatory disorders in the brain (including those associated with ischemic and hemorrhagic stroke, atherosclerosis, discirculatory encephalopathy, craniocerebral trauma);
- labyrinthine disorders (with such manifestations as nausea, vomiting, tinnitus , dizziness, etc.);
- migraine (for the prevention of exacerbations);
- Meniere's disease;
- violations of peripheral circulation (Raynaud's disease, thrombophlebitis, diabetic angiopathy, trophic ulcers, spasms and chilliness of limbs, syndrome of "intermittent" lameness, etc.);
- cerebrovascular disorders (as a support for tinnitus, vascular headaches, memory and attention disorders, irritability, etc.);
- kinetosis (for prevention).
Method of application of Cinnarizine
Duration of treatment, as well as daily dosage of the drug is selected individually. As a rule, 3-6 tablets are taken per day, and the treatment course is from several weeks to several months, to a noticeable therapeutic effect. Tablets should be taken after a meal or during a meal, with water and without chewing.
Side effects and special instructions for taking Cinnarizine
In most cases this drug is tolerated by patients normally. However, sometimes the following adverse reactions may occur during treatment:
- drowsiness during the day;
- nausea;
- pain in the abdomen;
- dry mouth ;
- skin rash;
- general weakness;
- dyspeptic phenomena;
- headache;
- fatigue, etc.
To eliminate side effects, you can try to reduce the dosage of the drug.
With prolonged use of Cinnarizine, the liver and kidneys should be monitored regularly, and blood tests performed. During the period of therapy, caution should be exercised when driving a car, as well as other activities requiring increased attention and speed of reactions.
Contraindications to the use of Cinnarizine:
- hypersensitivity to the components of the drug;
- pregnancy;
- the period of breastfeeding;
- Parkinson's disease (with extreme caution).