The main drawback of almost all effective diuretics (diuretics) is the excretion of potassium and magnesium from the body together with excess fluid. Veroshpiron belongs to a group of drugs that do not affect the concentration of these chemical elements. In some cases, it even helps to quickly restore it to an acceptable level.
Veroshpiron - composition
The active ingredient of the described medicament is spironolactone. This substance is a mineralocorticoid hormone antagonist, which is produced by the adrenal glands and promotes the accumulation of moisture and sodium salts in tissues (aldosterone). The drug Veroshpiron in various forms of release contains and auxiliary components:
- colloidal silicon dioxide;
- talc;
- magnesium stearate;
- lactose monohydrate;
- corn starch;
- sodium lauryl sulfate;
- titanium dioxide;
- gelatin;
- dye.
What is Veroshpiron for?
The main effect produced by spironolactone is a diuretic. This causes the most typical violation, from which helps Veroshpiron - stagnant phenomena of a different nature and origin. The presented drug is considered a safe means for removing excess fluid, because it does not interfere with electrolyte and salt balances in the body.
Veroshpiron - readings:
- chronic heart failure with edematous syndrome;
- Essential hypertension (spironolactone is included in the scheme of complex measures);
- secondary hyperaldosteronism on the background of liver cirrhosis , ascites, nephrotic lesions and other pathological conditions;
- paroxysmal myoplegia;
- hypomagnesemia;
- Connes syndrome;
- hypokalemia.
There is another area in which Veroshpiron is used - indications for use include hyperprolactinemia. Spironolactone has the property of reducing the intensity of adrenal hormone production. It prevents the increased production of prolactin, therefore it is often prescribed by gynecologists-endocrinologists with the corresponding disorders of the female reproductive system, including cystic, fibrous and diffuse mastopathy.
How to take Veroshpiron?
Portions and duration of treatment with spironolactone depend on the diagnosed disease and other associated pathologies. The drug Veroshpiron in some situations is administered in parallel with thiazide (loop) diuretics, which provides a more pronounced and quicker effect. Portions and duration of therapy are calculated only by a specialist. It is dangerous to drink Veroshpiron yourself - the dosage chosen incorrectly can lead to negative consequences. A common complication of amateur therapies is a severe disruption of kidney function.
How to take Veroshpiron with swelling?
In the case of chronic heart failure spironolactone is recommended to use for 5 days of 100 (maximum - 200) mg, divided by 2-3 times. Veroshpiron in swelling against the background of essential hypertension is prescribed in an amount of 50-100 mg once a day. Gradually (every 2 weeks) the dosage increases until it reaches 200 mg. The standard course of therapy is at least 14 days.
If congestion occurs due to cirrhosis of the liver, spironolactone is used in accordance with the ratio of potassium and sodium ions in urine. When this figure is more than 1, the daily portion of Veroshpiron is up to 100 mg. At a ratio of less than 1, spironolactone is recommended in an amount of 200-400 mg. Individually selected maintenance dose.
For treatment and differential diagnosis of hyperaldosteronism and nephrotic syndrome, a single dose is from 100 to 400 mg. Her doctor calculates on the basis of data on the form of the disease and the concentration of potassium in the blood. The daily dosage is taken for 1 or 2-4 times, depending on the purpose of therapy, the degree of edema and the tolerability of the medication.
Many patients are not interested in when to drink Veroshpiron - before meals or after, but eating significantly affects the effectiveness of the medication. Biological availability and digestibility of spironolactone increases if it enters the body along with food. Specialists recommend using the medication directly after eating and drinking it with 0.5 glasses of water.
How to take Veroshpiron for weight loss?
The described drug is a serious drug that eliminates severe swelling and stagnation. To use Veroshpiron for weight loss is impossible, it is not only inefficient, but also dangerous. Spironolactone does not affect the amount of fat deposits, but simply removes excess moisture from the body. If you use it as a means to lose weight or "drying", it can provoke diseases of the urinary system and kidneys.
Veroshpiron during pregnancy
When bearing spironolactone is contraindicated. This substance, having a high bioavailability, penetrates the placental barrier and enters the bloodstream of the child. Immediately after birth, too, you can not drink Veroshpiron - indications for use exclude and lactation. The active ingredient of the drug is absorbed into all biofluids and reaches a concentration of almost 100%, including breast milk. Veroshpiron in gynecology is used only in the treatment of hyperprolactinaemia and related diseases. This list includes mastopathy and endocrine infertility.
How long does Veroshpiron take?
The duration of the therapeutic course is calculated by the doctor after a thorough diagnosis. Do not take long to drink Veroshpiron - the use of a diuretic for more than 4 weeks can cause disturbances in electrolyte, salt and water metabolism. A frequent complication of such long-term treatment is urate diathesis or hyperuricuria. Diuretic Veroshpiron recommended to use for 5-15 days. In the presence of indications, a minimum maintenance dose of the drug is selected.
Veroshpiron - side effects
Negative phenomena with spironolactone are rare, but they include an extensive list of pathological conditions. Veroshpiron - side effects of the application:
- vomiting;
- diarrhea;
- nausea;
- gastritis;
- ulceration in the organs of the gastrointestinal tract;
- constipation;
- intestinal colic;
- pain in epigastrium;
- violations of liver functions;
- dizziness;
- ataxia;
- drowsiness;
- retardation;
- confusion of consciousness;
- lethargy;
- headache;
- thrombocytopenia;
- agranulocytosis;
- megaloblastosis;
- hypercreatininaemia;
- hyperuricemia;
- alkalosis;
- hyponatremia;
- metabolic acidosis;
- hyperkalemia;
- coarse voice;
- gynecomastia;
- dysmenorrhea;
- violation of the cycle;
- hirsutism;
- metrorrhagia;
- amenorrhea;
- itching of the skin;
- hives;
- fever;
- hypertrichosis;
- kidney failure;
- alopecia;
- convulsions;
- muscle spasms.
Veroshpiron - contraindications
There are diseases in which spironolactone is absolutely forbidden, and conditions when it can be used with caution. In the first case, you should replace Veroshpiron - the action of the drug will only do harm. Direct contraindications for use:
- hyperkalemia;
- Addison's disease ;
- renal insufficiency in the severe stage;
- hyponatremia;
- lactose intolerance;
- anuria;
- syndrome of impaired glucose or galactose uptake;
- pregnancy;
- deficiency of lactase;
- age up to 3 years;
- lactation;
- hypersensitivity to any ingredient in the drug.
In other situations, only the doctor decides how appropriate it is to prescribe Veroshpiron - indications for use may include the following diseases in which careful use of a diuretic is required:
- metabolic acidosis;
- hypercalcemia;
- diabetes;
- AV blockade;
- menstruation disorders;
- liver failure;
- diabetic nephropathy ;
- abnormal enlargement of the mammary glands;
- cirrhosis of the liver;
- elderly age.
Veroshpiron - analogues of the preparation
Replace the diuretic with medicines with the same effect. If Veroshpiron has indications for use, completely coinciding with the synonym, it is important to additionally verify the properties of the generic. It should prevent the leaching of magnesium and potassium salts, while maintaining the electrolyte balance in the norm. Veroshpiron - analogues with identical indications for use:
- Spironolactone (direct);
- Epletor;
- Renial;
- Eridanus;
- Dekriz;
- Epplepres;
- Inspra;
- Espiro.