Preparations of the sulfonamide group were invented quite a long time ago, and today they practically lost their significance, are inferior in effectiveness to modern antibiotics. Also, their limited use is due to the high toxicity and resistance of certain bacteria to them. But nevertheless at treatment of some diseases these agents are still applied.
Sulfanilamides are synthetic drugs that are active against a wide range of pathogens, including:
- streptococci;
- staphylococci;
- meningococci;
- E. coli ;
- cholera vibrio;
- chlamydia;
- diphtheria bacillus;
- actinomycetes and others.
The effect of drugs containing sulfonamides is based on their ability to disrupt the formation of acids produced by microorganisms and necessary for their development. These drugs are prescribed for various diseases: infections of the respiratory system and ENT organs, genito-urinary and gastrointestinal infections, dermatological infections, etc. Consider what preparations belong to the group of sulfonamides (names).
List of drugs-sulfonamides
- sulfonamide (streptocide) - practically not used today due to low efficiency and high toxicity;
- sulfadimidine (sulfadimezin) - a less toxic drug, but also not very active;
- sulfarabamide (urosulfan) - previously widely used in the treatment of infections of the genitourinary system;
- sulfadiazine (sulfazine) - more active than other sulfonamides, creates high concentrations in the blood;
- sulfamethoxazole - penetrates well into various organs and tissues;
- sulfadimethoxin - a long-acting agent;
- sulfamonomethoxin - relatively low toxicity;
- sulfadoxine - used to treat malaria in combination with antimetabolite
pyrimethamine; - sulfamethoxypyridazine - is used in the treatment of acute respiratory infections, pneumonia , bronchitis, etc .;
- sulfalene - an agent of super-long-acting;
- sulfaguanidine (sulgin) - effective in the treatment of intestinal infections;
- phtalylsulfatiazole (phthalazole) - creates high concentrations in the lumen of the intestine;
- sulfadiazine silver (dermazin) - a means for topical use;
- sulfasalazine - an intestinal anti-inflammatory and antirheumatic agent.